Neural Mechanisms of Anhedonia in Schizophrenia
نویسندگان
چکیده
منابع مشابه
Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors.
CONTEXT Loss of the capacity to experience pleasure (anhedonia) is a core clinical feature of schizophrenia. Although functional imaging techniques have been successful in identifying the neural basis of cognitive impairments in schizophrenia, no attempts to date have been made to investigate neural systems underlying emotional disturbances. OBJECTIVE To study the neural basis of emotional pr...
متن کاملAnhedonia and emotional experience in schizophrenia: neural and behavioral indicators.
BACKGROUND Emotional impairments such as anhedonia are often considered key features of schizophrenia. However, self-report research suggests that emotional experience in response to affect-eliciting stimuli is intact in schizophrenia. Investigation of neural activity during emotional experience may help clarify whether symptoms of anhedonia more likely reflect alterations of in-the-moment hedo...
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Anticipatory anhedonia in schizophrenia subjects L'anhédonie anticipatoire dans les schizo-phrénies Dear Editors, The distinction between the experience of pleasure related either to online experience in response to a specific stimulus (consummatory pleasure) or to future pleasurable activities (anticipatory pleasure) has been proposed by Klein [7] in a theoretical paper. Recently, accumulated ...
متن کاملNeurobiological mechanisms of anhedonia
Anhedonia refers to the reduced ability to experience pleasure, and has been studied in different neuropsychiatric disorders. Anhedonia is nevertheless considered as a core feature of major depressive disorder, according to DSM-IV criteria for major depression and the definition of melancholic subtype, and regarding its capacity to predict antidepressant response. Behavioral, electrophysiologic...
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Failures to replicate results in psychiatric genetics might be due to our inability to define the heritable phenotype. Instead of relying entirely on classical nosographical approaches, the use of a candidate symptom approach to identify more homogeneous forms of diseases among affected subjects and subclinical traits among first-degree relatives may increase genetic validity. Anhedonia may be ...
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ژورنال
عنوان ژورنال: JAMA
سال: 2001
ISSN: 0098-7484
DOI: 10.1001/jama.286.4.427